Construction Project Manager

We are building two pharmaceutical manufacturing facilities in North Texas, including ISO 7 / ISO 8 cleanrooms, pharmaceutical-grade HVAC systems, clean utilities, and highly regulated production environments.

Posted on
May 21, 2026

Construction Project Manager

North Texas | Full-Time | On-Site

The Opportunity

We are building two pharmaceutical manufacturing facilities in North Texas, including ISO 7 / ISO 8 cleanrooms, pharmaceutical-grade HVAC systems, clean utilities, and highly regulated production environments.

This is not a traditional commercial construction role.

We are seeking a hands-on Construction Project Manager with direct experience in regulated or technically complex facility construction who can own this project from pre-construction through commissioning and closeout. The ideal candidate brings pharmaceutical, cleanroom, biotech or regulated industrial facility experience and discipline to deliver a cGMP compliant building on schedule, within budget and for regulatory inspection from Day 1. After project completion, this role can transition into a long-term Facilities Manager leadership position overseeing ongoing operations, infrastructure, facilities maintenance, and future expansion projects. This role is ideal for someone who wants long-term ownership inside a growing organization.

What You’ll Own

Pre-Construction & Planning

  • Lead constructability reviews, value engineering and phasing plans for a cGMP facility build.
  • Collaborate with architects, MEP engineers, cleanroom vendors and the owner’s team to finalize design documents aligned with pharmaceutical regulatory requirements.
  • Establish project budget baseline, schedule and risk register prior to start of construction
  • Evaluate, select and contract specialty subcontractors with demonstrated experience in regulated or environments.

Construction Phase

  • Serve as the owner-side project manager throughout the full construction lifecycle.
  • Manage day-to-day field execution, subcontractor performance, RFIs, submittals, change orders, and schedule compliance
  • Oversee installation and coordination of cGMP-critical building systems, including:
  • Pharmaceutical-grade HVAC with HEPA filtration and pressure-differential controls
  • ISO 8 cleanroom envelope, finishes, and pass-throughs
  • Clean utilities: purified water (PW), clean steam, and clean compressed air/dry nitrogen (as applicable)
  • Building automation system (BAS) for environmental monitoring
  • Electrical systems, lighting, and emergency power for production areas
  • Maintain audit-ready project documentation throughout construction, including daily reports, inspection records, and commissioning prerequisites
  • Manage owner’s budget and forecast with rigorous cost-control discipline; approve pay applications and change orders

Commissioning, Qualification & Closeout

  • Coordinate with the owner’s commissioning and qualification (C&Q) team to develop Construction Turnover Packages (CTPs) and support IQ/OQ prerequisites
  • Oversee systems commissioning, punch-list resolution, and certificate of occupancy process
  • Deliver a complete project closeout package including as-builts, O&M manuals, spare parts, and regulatory-ready documentation

Required Qualifications

  • 5+ years of construction project management experience, with at least 2 years on pharmaceutical, biotech, cleanroom, semiconductor, or other regulated / technically complex facility projects
  • Demonstrated experience managing cGMP-critical building systems: HVAC, clean utilities, BAS, and classified environments
  • Direct experience managing MEP coordination on technically complex projects
  • Strong budget ownership and cost-control discipline on projects ranging from $5M–$20M
  • Proven subcontractor selection, contracting, and performance management skills
  • Proficiency with Procore, Buildertrend, or equivalent construction management software; Microsoft Project or Primavera P6 for scheduling
  • Strong written and verbal communication; ability to produce clear documentation for owner, design team, and regulatory purposes
  • Ability to work independently in a lean, fast-paced environment with high ownership

Strongly Preferred

  • Direct cGMP pharmaceutical or biotech facility construction experience (greenfield or bownfield)
  • Hands-on experience with ISO-classified cleanrooms (ISO 7 or ISO 8)
  • Experience participating in commissioning, qualification (IQ/OQ/PQ) or facility validation processes
  • Knowledge of ISPE baseline guides or similar pharmaceutical facility design standards.
  • Bachelor’s degree in Construction Management, Mechanical, Civil or Architectural Engineering or a related field.
  • PMP, CCM, or OSHA 30 certification

Why This Role

  • Build pharmaceutical facility from the ground up with full ownership over every phase
  • Direct access to company leadership and decision-makers throughout the project
  • Contribute to bringing new pharmaceutical products to market
  • Opportunity to grow into a Long-term Facilities & Engineering Management role post construction
  • Competitive compensation and full benefits package

Compensation & Benefits

  • Competitive salary based on experience
  • Medical, Dental, and Vision insurance
  • Paid Time Off and paid holidays
  • Career advancement opportunities
  • High-impact leadership role with long-term growth potential

Benefits:

  • Dental insurance
  • Health insurance
  • Paid time off
  • Vision insurance

Work Location: In person

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Thesis Pharmacy is a pharmacist-led compounding pharmacy committed to preparing individualized medications with accuracy, care, and respect for each patient’s unique needs.

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